Depression <\/a>is one of the most common symptoms of Cushing\u2019s disease and the link here is very clear. Not only is depression linked with stress \u2013 so that high levels of stress will cause you to feel exhausted and emotionally fatigued (not to mention potentially leading to adrenal fatigue) but also in that it might reduce levels of other key neurotransmitters.<\/p>\n\n\n\nIn particular, in this case, we are talking about serotonin. Serotonin is a feel-good hormone that is responsible for making us feel good about ourselves. On top of that, it is also a natural painkiller, a satiety hormone, and a chemical that has countless other important roles in the body.<\/p>\n\n\n\n
And as you might already have guessed, cortisol works as a serotonin agonist \u2013 meaning that it will reduce the amount of serotonin in your system simply by existing. This, therefore, means that you might find yourself feeling sad, exhausted, painful, and more.<\/p>\n\n\n\n
This is also why one of the primary ways to treat depression is by increasing the amount of serotonin in the system, which can be done with numerous different medications such as SSRIs (selective serotonin reuptake inhibitors).<\/p>\n\n\n\n
As you can see then, this condition can affect pretty much everything from your mood to your weight gain \u2013 you need to address it quickly.
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