{"id":6140,"date":"2019-04-30T03:33:57","date_gmt":"2019-04-30T03:33:57","guid":{"rendered":"https:\/\/simplyhealth.today\/?p=6140"},"modified":"2021-11-11T10:16:42","modified_gmt":"2021-11-11T10:16:42","slug":"14-alarming-facts-about-chronic-inflammatory-demyelinating-polyneuropathy-cidp","status":"publish","type":"post","link":"https:\/\/simplyhealth.today\/14-alarming-facts-about-chronic-inflammatory-demyelinating-polyneuropathy-cidp\/","title":{"rendered":"14 Alarming Facts About Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)"},"content":{"rendered":"\n
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A neurological disease that is capable of destroying a person from the inside out, CIDP is inflammatory, aggressive, and scary. A person who experiences the onset of this devastating disease will attest to the fact that it is a daunting prospect, no matter the age of diagnosis.<\/p>\n\n\n\n

During the chronic incarnation of the disease, irreparable and catastrophic damage is done to the body’s nerves and the surrounding tissues, leading to a whole host of life-changing complications.
<\/p>\n\n\n\n

A person\u2019s ability to move can be compromised to the point of altering their gait permanently, even leading to a lack of mobility altogether. The control a person is used to having over the movement of their arms and legs is likely to go. Sensory functionality decreases and disappears and what comes after this is likely to be a lingering feeling of numbness and tingling.<\/p>\n\n\n\n

Thankfully, the disease is rare, but here are some of the more alarming facts to do with CIDP.<\/p>\n\n\n\n

1.    Average Age of Onset<\/h3>\n\n\n\n

The average age for the onset of this disease is 50 years old, although the range stretches from as young as 35 to anything up to as long as a person might be expected to live. <\/p>\n\n\n\n

With 50 being the new 40, as they say, a person discovering that they are seriously ill can have devastating consequences that may be felt in different parts of their lives. At the age of 50, a person may expect to still have the best part of 2 decades in a working environment ahead of them, and the diagnosis <\/a>of this disease surely severs that expectation. At 50 many people are embarking on new relationships, such as the prevalence of divorce in the modern world. Some people reaching the age of 50 may well still be relatively new parents, as breakthroughs are constantly being made in the world of fertility.<\/p>\n\n\n\n

When all of these things are considered, the relatively low average age of onset can seem a pretty depressing fact to be aware of.<\/p>\n\n\n\n\n\n\n\n

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2.  Men Twice As Likely to be Affected<\/h3>\n\n\n\n

There are many illnesses and diseases which affect men and women in similar numbers. CIDP isn\u2019t one of those illnesses, as men are twice as likely to be affected as women. The reason for this isn’t fully understood, and whilst scientific studies have considered, examined, and investigated a range of factors including lifestyle<\/a>, working habits, and external factors, there have been few breakthroughs in determining why the prevalence in men is significantly higher than that in women. <\/p>\n\n\n\n

The lack of conclusive evidence leads one to believe that the reason for this difference is down to the genetic and hormonal differences between the genders, however, this is purely speculation. Whatever the reason for the disparity, be it explainable or a matter of coincidence, men are twice as likely to be affected by CIDP as women. <\/p>\n\n\n\n

The anecdotal reasoning that men are more reluctant to seek medical advice than women is therefore quite troubling, as they may go undiagnosed and untreated for longer than necessary.<\/p>\n\n\n\n\n\n\n\n

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3.  Early Symptoms<\/h3>\n\n\n\n

CIDP is notoriously difficult to diagnose, meaning that the early warning signs or related symptoms need to be monitored for a few months at least, in order for an accurate and educated diagnosis to be agreed upon. The earliest symptoms that a person may experience may seem mild, and easily attributable to much more trivial illnesses. <\/p>\n\n\n\n

If a person experience spells of clumsiness, for instance, it would not be out of the ordinary for a person to blame vertigo or even a mild viral infection<\/a>. The tingling that someone experiences in their feet in the early stages as well could be misinterpreted as prolonged pins and needles or even sciatica.<\/p>\n\n\n\n

The average onset of the symptoms means that it is likely that a person may expect to suffer from a range of different health concerns at this stage of their life, making the correlation and diagnosis of the early symptoms a bit of an uphill struggle when it comes to connecting the dots.<\/p>\n\n\n\n\n\n\n\n

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4. The Difference to Other Disorders<\/h3>\n\n\n\n

Although the disease does bear some similarities to other neurological conditions and shares common traits in terms of symptoms<\/a>, there are plenty of examples of differences in terms of early-onset, eventual symptoms, and possible treatment options that set CIDP to one side. A major difference is that with CIDP, it is unlikely that a patient will be able to recall any preceding illness or infection, whereas, with similar disorders, the lead-up infection can be pretty conclusive in determining what comes next. <\/p>\n\n\n\n

The symptoms of CIDP usually last up to 8 weeks, making them almost twice as long as the symptoms experienced by someone suffering from a similar disorder. Other disorders, such as GBS, may not bring about recurrences, however, the chronic nature of CIDP can leave a person with ongoing symptoms. <\/p>\n\n\n\n

One of the only useful tools in a doctor’s toolkit, when it comes to diagnosing this illness, is the fact that it is quite different from other illnesses that affect the body in a similar way.<\/p>\n\n\n\n\n\n\n\n

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5. Treatment Options<\/h3>\n\n\n\n

At the heart of treatment for CIDP is the need to bring about a reduction in inflammation<\/a>. This inflammation, which irritates the nerve, causing a catalog of symptoms, can be brought under control with a range of medications. <\/p>\n\n\n\n

Whilst no known cure exists for CIDP, any medication which brings about a normalization of the immune system can dramatically improve a person\u2019s life. Two drugs, recently legalized, aim to do just this, by decreasing the immune system actions which bring about nerve irritation and associated symptoms. The drugs, Gamunex and Privigen, are intravenously administered. Both of these medications contain potent antibodies which set to work trying to prevent any further nerve damage. <\/p>\n\n\n\n

Again, no matter how beneficial the treatment is with these drugs, it must be stressed that this does not amount to anything that could be considered \u2018a cure\u2019. Until a cure is found, sufferers will need to rely on the available treatments such as those mentioned above.<\/p>\n\n\n\n\n\n\n\n

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6. Diagnosis<\/h3>\n\n\n\n

As touched on earlier, CIDP <\/a>is particularly difficult to diagnose, especially in the early stages. One of the reasons for this is down to the fact that it is so rare. With the symptoms being progressive in many cases, an accurate diagnosis can only be reached following an elongated period of observation and assessment.<\/p>\n\n\n\n

This monitoring period is usually no less than one month and rarely any longer than two months, however, an upper estimate of 60 days can seem like 60 days too long when you’re waiting for news. Medical history is always taken when CIDP is suspected, with every minor detail given microscopic attention. Questions about symptoms must be as detailed in their posing, as they are in the answering. <\/p>\n\n\n\n

The relatively run-of-the-mill reflex test, which many doctors perform for many different reasons, can be quite conclusive where CIDP is suspected, given that an absence of reflexes, when experienced with weakness in the arms and legs can be a telltale sign for the presence of CIDP.<\/p>\n\n\n\n\n\n\n\n

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7. Impact of Diet<\/h3>\n\n\n\n

Given the inflammatory nature of the disease, it is not unusual for a doctor or medical professional to advise a person to try and adopt an anti-inflammatory diet. Whilst any change in diet is never an adequate substitution for the correct medications, it is thought that a person should try and avoid high sodium foods, foods that are high in both natural and processed sugars, processed foods, saturated fats, and trans fats. <\/p>\n\n\n\n

In practice, this means that a person with CIDP may benefit from a plant-based diet, concentrated around the consumption of an array of colorful fruits and vegetables. Lean meats and low mercury fish options, such as salmon may also be beneficial in the diet of a person with CIDP. <\/p>\n\n\n\n

Of course, any change in a person\u2019s diet<\/a>, particularly when that person is ill, should be reviewed with a medical professional and done so with an open mind and a thirst for new knowledge.<\/p>\n\n\n\n\n\n\n\n

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8. Summary of Symptoms<\/h3>\n\n\n\n

The final fact about CIDP could also potentially be the most alarming of all, as it gives a brief summary of the symptoms that an affected person can expect to suffer from. Clumsiness is common, meaning that injuries occurring as a result of this clumsiness are also a fairly regular occurrence. <\/p>\n\n\n\n

Difficulty swallowing is another issue with many CIDP sufferers have to endure, whilst double vision <\/a>and blurred peripheral vision give an indication of just how wide-reaching the disease can be, often affecting a person from head to toe and everywhere in between. <\/p>\n\n\n\n

As mentioned earlier, a loss or absence of reflexes, particularly in the infancy of the disease, can be experienced, as can foot drop, numbness, and a definite tingling sensation in the extremities. On top of all this, a person with CIDP is likely to feel incredibly fatigued, without any other reason than that their body is feeling the strain of the illness, and struggling to adjust.<\/p>\n\n\n\n\n\n\n\n

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9. CIDP Is an Auto-Immune Disorder<\/h3>\n\n\n\n

Medical professionals officially classify CIDP as an “auto-immune disorder<\/a>.” People with auto-
immune disorders experience adverse events regarding the interaction between their immune
system and their physiology.<\/p>\n\n\n\n


An Auto-immune disorder occurs when the immune system recognizes health cells as pathogenic
invaders, attacking the affected tissues, organs, nerves, or skeletal system in an attempt to drive out
what it mistakes for disease. <\/p>\n\n\n\n


Since CIDP is an auto-immune disorder, doctors don’t really understand the link between the
condition’s onset and the cause. With CIDP, the immune system attacks the myelin sheath around
the nerves, causing deterioration and neurological dysfunction in the affected individual. 
This process, known as “demyelination,” occurs slowly over time, with the patient’s symptoms
intensifying and growing over the years. Eventually, the patient may lose complete control over their
peripheral nervous system, requiring mechanical ventilation to survive. <\/p>\n\n\n\n


Myelin typically serves a function as axonal insulation, facilitating rapid communication with
neurons. As the sheath degrades, the patient begins to notice the onset of CIDP symptoms.<\/p>\n\n\n\n\n\n\n\n

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10. Peripheral Nervous System Issues Caused By CIDP<\/h3>\n\n\n\n

CIDP primarily affects the peripheral nervous system<\/a>. The PNS involves managing your motor skills
and the communication between the nervous system, your limbs, and your extremities (fingers and
toes). <\/p>\n\n\n\n


As a result, people affected by CIDP tend to notice a progression in their symptoms. Some of the
symptoms affecting the peripheral nervous system and its normal function include the following. <\/p>\n\n\n\n


\uf0b7 Progressive clumsiness.
\uf0b7 Difficulty swallowing (dysphagia).
\uf0b7 Problems with normal vision and occurrence of double vision.
\uf0b7 Improper foot placement when walking and foot drop.
\uf0b7 A slow loss in reflexes.
\uf0b7 Burning, tingling, or numbness in the fingers and hands.
\uf0b7 Unexplainable fatigue.<\/p>\n\n\n\n


The symptoms of CIDP usually occur on both sides of the patient’s body. For instance, the patient
may notice pain and burning sensation in both arms or legs. 
Some people also report the onset of changes to their sensory functions, such as numbness and
tingling, But without changes to their normal walking gait or posture.<\/p>\n\n\n\n\n\n\n\n

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11. The Link Between CIDP and Guillain-Barre syndrome (GBS)<\/h3>\n\n\n\n

CIDP is an auto-immune disorder, and it’s often confused with other auto-immune diseases
producing similar symptoms. However, there is convincing research showing a relation between
CIDP and Guillain-Barre Syndrome<\/a> (GBS). <\/p>\n\n\n\n


GBS is a short-term condition, or an “acute” condition, meaning that it comes and goes. GBS also
affects the peripheral nervous system, producing problems with the normal communication of
nerves and the muscular system. <\/p>\n\n\n\n


However, the significant difference between GBS and CIDP is that GBS patients eventually
experience a subsiding of their symptoms. Some individuals may experience the condition during
young adulthood, and it fades away after a few years, never occurring again. <\/p>\n\n\n\n


However, some individuals may encounter “triggers” later in life that spurs a new round of the
condition’s symptoms appearing in the affected person. CDIP is a “chronic” condition, meaning that
it never goes away. Once diagnosed, the patient experienced a slow degradation of the myelin
sheath, eventually resulting in paralysis.<\/p>\n\n\n\n\n\n\n\n

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12. What to Expect with CIDP<\/h3>\n\n\n\n

So, what can patients expect from their experience with CIDP? There are two paths patients can
take; treatment or no treatment. Due to the high cost of medical care associated with the condition,
many people don’t get the treatment they need until the advanced stages of the disorder.\u00a0<\/p>\n\n\n\n


If you decide to forego the treatment for CIDP, or you don’t get a diagnosis early enough, you run
the risk of the condition spreading faster than if you get treatment as you notice symptoms arise.
Symptoms may take months to emerge and intensify to the point where people take action and seek
medical care.<\/p>\n\n\n\n


There is potential that your doctor and physiotherapist<\/a> can dramatically slow the rate of progression
of the disorder and its effects on your body. However, rapid diagnosis and immediate treatment are
the only ways to ensure a better quality of life with living with CIDP. <\/p>\n\n\n\n


Patients may be fine for months after treatment and then relapse into pain and discomfort as
symptoms progress. Speak to your doctor about the right treatment plan for the stage of the
disorder.<\/p>\n\n\n\n\n\n\n\n

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13. How many Americans Have CIDP?<\/h3>\n\n\n\n

CIDP is a rare condition. According to studies, the disease affects around 40,000 people in the United
States. Considering a population of 350+ million in the US, it’s a very rare disorder. As a result, many
doctors may have problems in the diagnosis of your condition. <\/p>\n\n\n\n

Your physician may take bloodwork to look for inflammatory markers and immune system integrity.
Doctors often confuse CIDP with other conditions like ALS and MS due to its effects on the nervous
system. Patients that receive an incorrect diagnosis may have a harder time treating the disease<\/a>. <\/p>\n\n\n\n


If you get a diagnosis of CIDP, it’s always a good idea to get a second opinion from another specialist.
CIDP usually occurs with progressive symptoms, but it can also show up with relapsing-remitting,
stepwise, or gradually progressive symptoms, making it challenging for doctors to diagnose.<\/p>\n\n\n\n


Speak to your doctor and ask them to refer you to a specialist if you suspect you might be dealing
with the onset of CIDP.<\/p>\n\n\n\n\n\n\n\n

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14. Will Patients Ever Recover from CIDP?<\/h3>\n\n\n\n

As mentioned, CIDP can come with progressive, relapsing-remitting, stepwise, or gradually
progressive symptoms. Some patients have a similar experience to GBS, where the condition flares
and then fades for years. <\/p>\n\n\n\n


However, most patients usually experience a gradually recurring experience of symptoms as they
age. As patients age, they may also experience complications for other disorders like osteoarthritis
and rheumatoid arthritis<\/a>, another auto-immune disorder affecting the skeletal system.<\/p>\n\n\n\n


Some patients recover better than others, and it depends largely on your immune system and the
strength of the auto-immune response to the condition. Those immunocompromised individuals
typically have a harder time with the effects of the disorder than those with stronger immune
system responses. <\/p>\n\n\n\n


Unfortunately, because it’s a chronic medical disorder, the patient will never officially recover from
CIPD. The condition may subside for years, encoded in your genetics and your immune response.
You might go for years without any problems before triggers flare the disorder. <\/p>\n\n\n\n


Most patients experience a steady progression of their symptoms and an eventual loss of
communication between the PNS and the muscular system.<\/p>\n\n\n\n\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

A neurological disease that is capable of destroying a person from the inside out, CIDP is inflammatory, aggressive, and scary. A person who experiences the onset of this devastating disease will attest to the fact that it is a daunting prospect, no matter the age of diagnosis. 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