5. Stiff joints.
As mentioned, bleeding between the joints is one of the most common signs of hemophilia. This bleeding not only causes pain, but it can also cause stiffness in the joints; especially when bleeding within the spaces between the joints occurs frequently. Frequent bleeding between the joints can lead to chronic swelling within the space, as blood flow puts high levels of pressure on the joints. As a result of this swelling, the joints can become deformed; more specifically, the cartilage that surrounds the bones that come together in the joints can become damaged and deformed.
Cartilage cushions and absorbs shock in the bones that form joints; when it is damaged and deformed, stiffness can occur. This stiffness can be painful and can reduce mobility.
Joints that are most commonly affected include the knees, elbows, and ankles; however, any joint can become stiff as a result of hemophilia.