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8. Triggers
The exact cause of sarcoidosis has never been confirmed. The risk factors have been well-studied, but the actual etiology is yet to be determined. That being said, some experts have proposed the possibility that sarcoidosis develops as the result of the immune system responding to an unidentified substance. There have been a few studies looking into these claims. Some have found that dust is the substance to blame.
Others, however, found a closer correlation between chemicals and infectious agents. One particularly interesting study suggested that the immune system may be having an atypical reaction to the proteins in the body. They have stated that this very reaction may be what leads to the development of granulomas provided that the patient has a genetic predisposition to sarcoidosis.